Ensure that the DPG2 and the eval board are detected in the Device Manager:
If the two devices do not appear as shown, reinstall the latest version of DPGDownloader.
Verify that the appropriate DLL for your evaluation board is present in: C:\Program Files (x86)\Analog Devices\DPG\ the file is named: AnalogDevices.DPG.EvalBoard.ADXXXX.dll where XXXX is the part number of your evaluation board. If the file is not present install the DAC update file for your evaluation board.